DrugDashboards

Oxycodone and Acetaminophen

Oxycodone and Acetaminophen · OXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1 · Tablet · Oral · Epic Pharma, LLC

NDC 42806-0114-01 · 100 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

16 companies supply this market — deep enough that no single failure threatens the supply. The price has held steady around $0.0884 per unit over the past year.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 42858-0102-50) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of saleⓘ
$0.1680per unit
middle half $0.1332–$0.1976 · 5,510 plans · Jan 1, 2026
Est. net of rebatesⓘ
≈ $0.1680
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 3 · prior auth 2% · step therapy 0% · qty limit 95%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 4 quarters since 2024.

NADAC price per unit

$0$0.05$0.1$0.15Feb 2019May 2022$0.0884
40 price points · per · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for oxycodone and acetaminophen (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA203864
TE code
AA
Approval date
Jul 2, 2018
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation — Acetaminophen; Oxycodone Hydrochloride, Tablet, 325 mg; 10 mg (NDC 60951-712-70)Nov 3, 2025
  • Planned discontinuation — Acetaminophen; Oxycodone Hydrochloride, Tablet, 325 mg; 2.5 mg (NDC 60951-701-70)Nov 3, 2025
  • Planned discontinuation — Acetaminophen; Oxycodone Hydrochloride, Tablet, 325 mg; 5 mg (NDC 60951-602-70)Nov 3, 2025
  • Planned discontinuation — Acetaminophen; Oxycodone Hydrochloride, Tablet, 325 mg; 5 mg (NDC 60951-602-85)Nov 3, 2025
  • Planned discontinuation — Acetaminophen; Oxycodone Hydrochloride, Tablet, 325 mg; 7.5 mg (NDC 60951-700-70)Nov 3, 2025

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Oxycodone and Acetaminophen (Tablet)

LabelerStrengthFirst seenLast seen
Asclemed USA, Inc.OXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Asclemed USA, Inc.OXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Bryant Ranch PrepackOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Bryant Ranch PrepackOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Camber Pharmaceuticals, Inc.OXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Camber Pharmaceuticals, Inc.OXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Camber Pharmaceuticals, Inc.OXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Camber Pharmaceuticals, Inc.OXYCODONE HYDROCHLORIDE 2.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Proficient Rx LPOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Alvogen, Inc.OXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Alvogen, Inc.OXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Alvogen, Inc.OXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
American Health PackagingOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
American Health PackagingOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
American Health PackagingOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals LLCOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Asclemed USA, Inc.OXYCODONE HYDROCHLORIDE 2.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Aurolife Pharma, LLCOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Aurolife Pharma, LLCOXYCODONE HYDROCHLORIDE 2.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Aurolife Pharma, LLCOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Aurolife Pharma, LLCOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
AvPAKACETAMINOPHEN 325 mg/1; OXYCODONE HYDROCHLORIDE 10 mg/1Jul 15, 2026Sep 2, 2026
AvPAKOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
AvPAKOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Direct RxOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Direct RxACETAMINOPHEN 325 mg/1; OXYCODONE HYDROCHLORIDE 7.5 mg/1Jul 15, 2026Sep 2, 2026
Direct_RxOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Direct_RxOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Epic Pharma, LLCOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Epic Pharma, LLCOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Epic Pharma, LLCOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Eywa Pharma IncOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Eywa Pharma IncOXYCODONE HYDROCHLORIDE 10 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Eywa Pharma IncOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
FH2 Pharma LLCOXYCODONE HYDROCHLORIDE 2.5 mg/1; ACETAMINOPHEN 300 mg/1Aug 26, 2026Sep 2, 2026
FH2 Pharma LLCOXYCODONE HYDROCHLORIDE 7.5 mg/1; ACETAMINOPHEN 300 mg/1Aug 26, 2026Sep 2, 2026
Forte Bio-Pharma LLCOXYCODONE HYDROCHLORIDE 5 mg/1; ACETAMINOPHEN 300 mg/1Aug 26, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Oxycodone and Acetaminophen — NDC 42806-0114-01," retrieved September 3, 2026, https://drugdashboards.com/drug/42806011401.

Free to cite with attribution — see how the data is put together.