The short version
18 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Carbidopa and Levodopa
Carbidopa and Levodopa · CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 · Tablet · Oral · Aphena Pharma Solutions - Tennessee, LLC
NDC 71610-0647-60 · 90 TABLET in 1 BOTTLE · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 78206-0168-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$1.45per unit
middle half $1.45–$1.45 · 2 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $1.45
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 0%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for carbidopa and levodopa (oral solid) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- Aphena Pharma Solutions - Tennessee, LLCUnited Statesrepack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA214092
- TE code
- AB
- Approval date
- May 7, 2021
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Carbidopa and Levodopa (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Bryant Ranch Prepack | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Mayne Pharma International Pty Ltd | LEVODOPA 250 mg/1; CARBIDOPA 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| A-S Medication Solutions | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd., | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd., | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Advagen Pharma Ltd., | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvKARE | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Camber Pharmaceuticals, Inc. | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | CARBIDOPA HYDRATE 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | CARBIDOPA HYDRATE 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Dr. Reddy's Laboratories Inc | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Dr. Reddy's Laboratories Inc | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Dr. Reddy's Laboratories Inc | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | CARBIDOPA HYDRATE 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | CARBIDOPA HYDRATE 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mayne Pharma International Pty Ltd | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mayne Pharma International Pty Ltd | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Organon LLC | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Proficient Rx LP | CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Carbidopa and Levodopa — NDC 71610-0647-60," retrieved September 3, 2026, https://drugdashboards.com/drug/71610064760.
Free to cite with attribution — see how the data is put together.