DrugDashboards

Carbidopa and Levodopa

Carbidopa and Levodopa · CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1 · Tablet · Oral · Dr. Reddy's Laboratories Inc

NDC 75907-0021-01 · 100 TABLET in 1 BOTTLE · ANDA · View full market →

The short version

18 companies supply this market — deep enough that no single failure threatens the supply. The price is down 22% over the past year, to $0.1094 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1094per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$0.1116per TABweighted avg manufacturer price $0.0638 · Aug 1, 2026102% of what pharmacies pay — higher than 57% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 52817-0392-10) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.1892per unit
middle half $0.0895$0.2565 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.1892
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 9 quarters since 2024.

NADAC price per unit

$0$0.05$0.1$0.15Jun 2024Sep 2026$0.1094
28 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$3.28
#90 count
$9.84

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$61,718
1,966 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for carbidopa and levodopa (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA073607
TE code
AB
Approval date
Aug 28, 1992
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Carbidopa and Levodopa (Tablet)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackCARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 3, 2026
Mayne Pharma International Pty LtdLEVODOPA 250 mg/1; CARBIDOPA 25 mg/1Aug 20, 2026Sep 3, 2026
A-S Medication SolutionsCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Advagen Pharma Ltd.,CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Advagen Pharma Ltd.,CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
Advagen Pharma Ltd.,CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingCARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedCARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
AvKARECARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
AvKARECARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
AvKARECARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
AvPAKCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.CARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.CARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCCARBIDOPA HYDRATE 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCCARBIDOPA HYDRATE 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories IncCARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories IncCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories IncCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsCARBIDOPA HYDRATE 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsCARBIDOPA HYDRATE 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Mayne Pharma International Pty LtdCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Mayne Pharma International Pty LtdCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsCARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.CARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Organon LLCCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Proficient Rx LPCARBIDOPA 10 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Proficient Rx LPCARBIDOPA 25 mg/1; LEVODOPA 100 mg/1Jul 15, 2026Sep 2, 2026
Proficient Rx LPCARBIDOPA 25 mg/1; LEVODOPA 250 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Carbidopa and Levodopa — NDC 75907-0021-01," retrieved September 3, 2026, https://drugdashboards.com/drug/75907002101.

Free to cite with attribution — see how the data is put together.