The short version
16 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
lisinopril and hydrochlorothiazide · LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 · Tablet · Oral · Almatica Pharma Inc.
NDC 52427-0436-90 · 90 TABLET in 1 BOTTLE · NDA · View full market →
16 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Not scored — fragility is computed for NADAC-priced NDCs.
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Actavis Pharma, Inc. | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Actavis Pharma, Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Actavis Pharma, Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Advanced Rx Pharmacy of Tennessee, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Almatica Pharma Inc. | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Almatica Pharma Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Almatica Pharma Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| GSMS, Incorporated | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| GSMS, Incorporated | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| GSMS, Incorporated | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Legacy Pharmaceutical Packaging, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Legacy Pharmaceutical Packaging, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Legacy Pharmaceutical Packaging, LLC | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| NuCarePharmaceuticals, Inc. | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Zestoretic — NDC 52427-0436-90," retrieved September 3, 2026, https://drugdashboards.com/drug/52427043690.
Free to cite with attribution — see how the data is put together.