The short version
16 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Lisinopril and Hydrochlorothiazide
Lisinopril and Hydrochlorothiazide · HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 · Tablet · Oral · Coupler LLC
NDC 67046-0433-03 · 30 TABLET in 1 BLISTER PACK · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 68180-0519-02) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$0.1108per unit
middle half $0.0809–$0.1590 · 5,496 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $0.1108
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 1 · prior auth 0% · step therapy 0% · qty limit 23%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.2%chance of a new FDA shortage posting for lisinopril and hydrochlorothiazide (oral solid) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- repack
- Coupler LLCUnited Statesrepack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA077912
- TE code
- AB
- Approval date
- Sep 27, 2006
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Lisinopril and Hydrochlorothiazide (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Actavis Pharma, Inc. | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Actavis Pharma, Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Actavis Pharma, Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Aurobindo Pharma Limited | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 20, 2026 | Sep 3, 2026 |
| Advanced Rx Pharmacy of Tennessee, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Almatica Pharma Inc. | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Almatica Pharma Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Almatica Pharma Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| GSMS, Incorporated | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| GSMS, Incorporated | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| GSMS, Incorporated | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Legacy Pharmaceutical Packaging, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Legacy Pharmaceutical Packaging, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Legacy Pharmaceutical Packaging, LLC | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Lupin Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Northwind Health Company, LLC | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals,Inc. | LISINOPRIL 20 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| NuCarePharmaceuticals, Inc. | LISINOPRIL 10 mg/1; HYDROCHLOROTHIAZIDE 12.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| PD-Rx Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 25 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 20 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | HYDROCHLOROTHIAZIDE 12.5 mg/1; LISINOPRIL 10 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Lisinopril and Hydrochlorothiazide — NDC 67046-0433-03," retrieved September 3, 2026, https://drugdashboards.com/drug/67046043303.
Free to cite with attribution — see how the data is put together.